The ultrastructure of Leishmania donovani.
نویسنده
چکیده
منابع مشابه
Visceral Leishmaniasis
General Considerations The most common etiologic agents of VL are 3 species of the L. donovani complex: Leishmania donovani donovani and Leishmania donovani infantum in the Indian subcontinent, Africa, China, the Mediterranean littoral, and the Middle East; and Leishmania donovani chagasi in South America. (Hereafter, organisms will be identified only by genus and species; eg, L. donovani for L...
متن کاملValidation of a β-ME ELISA for Detection of Anti Leishmania donovani Antibodies in Eastern Sudan
Background: A β-mercaptoethnol (β-ME)-treated promastigote antigen of L. donovani was successfully employed in direct agglutination test (DAT) for the diagnosis of visceral leishmaniasis (VL). Objective: The β-ME-treated antigen was further incorporated into an enzyme-linked immunosorbent assay set-up (β-ME ELISA) and evaluated for VL diagnosis against outcome of reference freeze-dried DAT (FD-...
متن کاملComparative in-silico genome analysis of Leishmania (Leishmania) donovani: A step towards its species specificity
Comparative genome analysis of recently sequenced Leishmania (L.) donovani was unexplored so far. The present study deals with the complete scanning of L. (L.) donovani genome revealing its interspecies variations. 60 distinctly present genes in L. (L.) donovani were identified when the whole genome was compared with Leishmania (L.) infantum. Similarly 72, 159, and 265 species specific genes we...
متن کاملLeishmania donovani lacking the Golgi GDP-Man transporter LPG2 exhibit attenuated virulence in mammalian hosts.
Surface phosophoglycans such as lipophosphoglycan (LPG) or proteophosphoglycan (PPG) and glycosylinositol phospholipids (GIPLs) modulate essential interactions between Leishmania and mammalian macrophages. Phosphoglycan synthesis depends on the Golgi GDP-mannose transporter encoded by LPG2. LPG2-null (lpg2(-)) Leishmania major cannot establish macrophage infections or induce acute pathology, wh...
متن کاملQualitative and Semi-Quantitative Comparison of an Rk39 Strip Test and Direct Agglutination Test for Detection of Anti-Leishmania Donovani Antibodies in the Sudan
Background: Until now, the comparison of the rK39 strip test (RKT) and direct ag-glutination test (DAT) for detection of visceral leishmaniasis (VL) is exclusively based on either positive or negative qualification of the reaction outcome. Objective: In this study, we compared the diagnostic performance of RKT and DAT for VL both qualitatively and semi-quantitatively. Methods: For comparison ba...
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عنوان ژورنال:
- The Journal of parasitology
دوره 42 2 شماره
صفحات -
تاریخ انتشار 1956